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The active ingredients are pseudoephedrine (pseudoephedrine hydrochloride) and cetirizine (cetirizine dihydrochloride).
1 tablet contains 5 mg cetirizine dihydrochloride (as an immediate release form) and 120 mg of pseudoephedrine hydrochloride (as a prolonged release form).
Excipients : immediate release layer : lactose monohydrate , microcrystalline cellulose, croscarmellose sodium, colloidal anhydrous silica, magnesium stearate; Sustained release layer: hypromellose, microcrystalline cellulose, colloidal anhydrous silica, magnesium stearate; Coating Opadry Y-1-7000 white: hypromellose, titanium dioxide (E 171), macrogol 400.
dosage
Always use this medicine exactly as described in the package leaflet or as directed by your doctor or pharmacist.
oral drug.
Cirrus should be taken with or without food.
Tablets must not be crushed, chewed, divided or crushed. Swallow whole.
If symptoms worsen or persist after 5 days, contact your doctor.
The drug is allowed to use no more than 2-3 weeks.
Adolescents over 12 years of age and adults: 1 tablet 2 times a day (morning and evening).
Patients with moderate renal or hepatic insufficiency: the dose should be reduced to 1 tablet per day.
action
Cirrus Duo contains 2 active ingredients responsible for antiallergic (cetirizine) and stuffy nose (pseudoephedrine) effect. Pseudoephedrine constricts the blood vessels in the nasal mucosa. Cirrus Duo relieves the symptoms associated with perennial and seasonal allergic rhinitis.
testimony
Symptomatic treatment of seasonal and year-round allergic rhinitis (nasal congestion, sneezing, runny nose, itching in the nose and conjunctiva).
contraindications
Do not use Cirrus Duo:
If you are allergic to the active ingredients of this medicine (cetirizine, pseudoephedrine), ephedrine, piperazine or its derivatives, or any of the other ingredients of this medicine,
if you suffer from severe arterial hypertension, severe coronary heart disease, severe renal failure, decompensated hyperthyroidism, severe cardiac arrhythmias, pheochromocytoma, glaucoma, increased intraocular pressure,
if you have moisture retention
if you have had a stroke
if you are at high risk of hemorrhagic stroke
If you are taking medications such as dihydroergotamine or MAO inhibitors (or have taken MAO in the past 2 weeks),
in persons under the age of 12 years.side effects
Like all medicines, this drug can cause side effects, although not everyone gets them.
Common side effects (may affect up to 1 in 100 people):
insomnia, nervousness, drowsiness,
headache, dizziness,
accelerated heartbeat
dry mouth
Nausea,
weakness.
Uncommon side effects (may affect up to 1 in 1,000 people):
Stimulation,
Fear.
Rare side effects (may affect up to 1 in 10,000 people):
convulsions, tremor
Heart arythmy,
dry skin, rash, urticaria, increased sweating
high blood pressure,
hypersensitivity reactions,
hallucinations
Pallor,
painful/difficulty urinating.
Very rare side effects (less than 1 in 10,000 people):
taste disorder
drug rash
angioedema
circulatory collapse,
psychotic disorders.
Not known:
blurred vision, disturbance of accommodation, abnormal pupillary dilation, eye pain, decreased vision, abnormal visual light tolerance,
erectile dysfunction,
heartbeat,
dyspnea,
Skin reactions with fever and pimples.
Warnings and Precautions
Care should be taken if the patient is diagnosed with: diabetes mellitus, hyperthyroidism, arterial hypertension, coronary heart disease, cardiac arrhythmia, moderate renal or hepatic insufficiency.
Use with caution in the elderly if the patient is taking sympathomimetics (eg, nasal decongestants, appetite suppressants), TLPD, antihypertensive drugs, drugs that suppress CNS function, cardiac glycosides (digoxin), in patients with prostatic hyperplasia or difficulty in urination.
Caution should be exercised if the patient has risk factors for hemorrhagic stroke.
The combination of pseudoephedrine and NSAIDs can lead to an increase in blood pressure.
Before using the drug in patients with impaired renal or hepatic function, consult your doctor.
The drug contains lactose – discuss with your doctor the use of the drug in case of intolerance to some sugars.
Keep the drug away from children.
use of other medicines
Tell your doctor or pharmacist about all medicines you are taking or have recently taken and the doctor you plan to take, including those sold without a prescription.
Cirrus Duo may interact with:
MAO inhibitors and dihydroergotamine (the combination of these drugs with Cirrus Duo is contraindicated),
TLPD,
vasoconstrictor drugs (bromocriptine, ergotamine),
Nasal decongestants (phenylephrine, ephedrine),
Medicines that lower blood pressure (such as beta-blockers)
cardiac glycosides (digoxin, digitoxin),
CNS depressants, such as tranquilizers
antacids and proton pump inhibitors,
theophylline,
ritonavir
NLPZ.
Taking the drug with food and drink
Cirrus Duo can be used during or between meals.pregnancy and breastfeeding period
Cirrus Duo should not be used during pregnancy and lactation (cetirizine and pseudoephedrine pass into breast milk).
Impact on laboratory tests
The drug may affect the results of skin allergy tests.
The use of the drug in children and adolescents
Do not use the drug for persons under 12 years of age.
driving and working machines
Cirrus Duo may cause drowsiness and drowsiness. If these symptoms appear, do not drive or operate machinery.
The individual response to the drug and the possibility of side effects should be taken into account.
In the recommended doses, cetirizine did not have a significant effect on psychophysical fitness.
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